Ketamine for migraines

Ketamine could be your breakthrough

Ketamine treatments can reduce the frequency and severity of debilitating migraine headaches. Intense sufferers have reported being able to function normally for several years with controlled migraines, thanks to ketamine.

Migraines are a big headache

Each year, American workers miss over 113 million workdays due to migraines, making chronic illness the sixth most debilitating. More than mere headaches, migraines often cause intense pain, hypersensitivity, and nausea, among other symptoms.

Despite these staggering statistics, migraines are notoriously difficult to treat. However, recent research shows that ketamine reduces both the frequency and duration of migraines and also reduced the number of other medications needed in acute migraine attacks.

Fun-fact:

John Lilly, a neuroscientist pioneer in researching early dolphin-to-human communication and dolphin intelligence, experimented with ketamine to cure his Migraine headaches.

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Each year, American workers miss over 113 million workdays due to migraines, making chronic illness the sixth most debilitating in the world

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90% of migraine sufferers cannot function normally during an attack

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A study of 61 patients found that almost 75 percent experienced an improvement in their migraine intensity after a three to seven day course of inpatient treatment with ketamine

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71% with refractory migraines report relief after ketamine

Pain and migraine research

Study

Summary

Migraines

Ketamine for Refractory Headache: A Retrospective Analysis

Ketamine provides potent analgesia in subanesthetic doses in chronic pain, and limited data suggest it may alleviate headache in some patients. Maximum improvement occurred 4.56 days (mean) into treatment. Ketamine was associated with short-term headache relief with tolerable adverse events.

Migraines

Ketamine may help treat migraine pain unresponsive to other therapies

The study of 61 patients found that almost 75 percent experienced an improvement in their migraine intensity after a three- to seven-day course of inpatient treatment with ketamine.

Pain

Plasma inflammatory cytokines and treatment-resistant depression with comorbid pain: improvement by ketamine

Ketamine can address both physical and psychological pain. It's widely used as an analgesic, and many people with depression also experience physical pain. This study found that ketamine had a stronger anti-depressant effect in patients with treatment-resistant depression (TRD) and pain than with TRD alone.

Pain

Ketamine Infusions for Chronic Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials

A metanalysis of studies examining ketamine's effect on pain. Among 696 studies assessed for eligibility, 7 met inclusion criteria. Evidence suggests that IV ketamine provides significant short-term analgesic benefit in patients with refractory chronic pain, with some evidence of a dose–response relationship.

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