Ketamine for holistic wellbeing

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You deserve to thrive

If traditional treatments have been less effective than you would like, ketamine may be the solution that gets you over that hump and allows you to break through to the level of well-being you deserve. 

Low-dose ketamine offers safe, proven treatment to tackle stubborn, long-term symptoms and feel better fast. Clinical data proves that ketamine provides measurable relief to many who haven’t found success with other interventions.

Become your best self

In addition to tackling specific, measurable symptoms, it provides overall benefits to your general wellbeing.

During sessions, ketamine allows you to journey into your subconscious and uncover unique insights into your own mind, memories, and self-awareness.  People commonly report feeling less heavy, increased motivation, and more connectedness to others and their universe than ever before. 

If you’ve tried at least two other methods of treatment with inadequate relief, let ketamine help you break through to the next level of wellness.

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After their first three weeks of treatment, more than 80% of patients report at least a 50% reduction in symptoms

We are the Northwest’s most experienced ketamine clinic, providing over 21,000 treatments since 2017

Ketamine research

Effect
Study
Level of evidence
Magnitude of effect
Summary
Anesthesia
Pharmacologic effects of CI-581, a new dissociative anesthetic, in man.
One of the first studies looking at the anesthetic properties of ketamine
Anxiety
Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial
Many patients with social anxiety disorder (SAD) experience inadequate symptom relief from available treatments. Ketamine is a potent N-methyl-d-aspartate receptor antagonist with a potentially novel mechanism of action to treat anxiety disorders. This proof-of-concept trial provides initial evidence that ketamine may effectively reduce anxiety
Anxiety
Safety and efficacy of maintenance ketamine treatment in patients with treatment-refractory generalised anxiety and social anxiety disorders
This study sought to evaluate the effect of weekly ketamine treatments for three months on anxiety ratings, safety, and tolerability in patients with treatment-refractory generalized anxiety disorder (GAD) and social anxiety disorder (SAD), and subsequent assessment of remission post-treatment. Patients reported marked improvements in functionality and in their personal lives. Maintenance ketamine may be a therapeutic alternative for treatment-refractory GAD/SAD patients
Depression
Efficacy of ketamine therapy in the treatment of depression
Ketamine acts faster than traditional anti-depressants
Depression
Ketamine for Treatment-Resistant Mood Disorders
Intravenous ketamine administration for treatment-resistant depression (TRD) is generally safe and well-tolerated when administered by trained professionals. An initial case series of 10 subjects with TRD who received six open-label ketamine infusions over 12 days found that, throughout treatment, depressive symptoms were reduced by an average of 85%
Depression
Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression: a meta-analysis of randomized clinical trials
Meta-analysis revealed rapid and robust anti-depressant effects of single-dose ketamine in treatment-resistant depression (TRD) patients. By pooling data from RCTs, we showed for the first time that repeated ketamine administration is effective in sustaining initial anti-depressant effects observed after single dosing
Depression
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders
N/A
Several studies now provide evidence of ketamine hydrochloride's ability to produce rapid and robust anti-depressant effects in patients with mood and anxiety disorders that were previously resistant to treatment. Despite the relatively small sample sizes, lack of longer-term data on efficacy, and limited data on safety provided by these studies, they have led to increased use of ketamine as an off-label treatment for mood and other psychiatric disorders
Depression
Ketamine as a novel treatment for major depressive disorder and bipolar depression: a systematic review and quantitative meta-analysis
The quantitative meta-analysis showed that ketamine significantly reduced depressive symptoms. The large and statistically significant effect of ketamine on depressive symptoms supports a promising, new, and effective pharmacotherapy with rapid onset, high efficacy, and good tolerability
Depression
Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)
This study aimed to assess the effectiveness of a broad range of subanesthetic IV ketamine doses in the acute (72 h) treatment of TRD patients when added to stable anti-depressant therapy. The results suggest evidence for the anti-depressant efficacy of the 0.5 mg/kg and 1.0 mg/kg subanesthetic doses of IV ketamine and no clear or consistent evidence for clinically meaningful efficacy of lower doses of IV ketamine
Depression, fast-acting
Ketamine and the Future of Rapid-Acting Antidepressants
The therapeutic onset of traditional anti-depressants is delayed by several weeks. Many depressed patients fail to respond to treatment altogether. In contrast, subanesthetic ketamine can rapidly alleviate symptoms of depression within hours of a single administration, even in patients who are considered treatment-resistant
Depression
Oral Ketamine for Depression: A Systematic Review
A small number of clinical studies assessed the anti-depressant effects of oral ketamine. Initial results suggest that oral ketamine has significant anti-depressant effects with good overall tolerability; however, anti-depressant effects are not as rapid as those associated with IV ketamine
Neroplasticity
(R)-Ketamine Rapidly Ameliorates the Decreased Spine Density in the Medial Prefrontal Cortex and Hippocampus of Susceptible Mice After Chronic Social Defeat Stress
Ketamine facilitates neuronal growth (in mice)
Neroplasticity
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation
Ketamine re-establishes and strengthens neural connections via dendrites
OCD
Randomized Controlled Crossover Trial of Ketamine in Obsessive-Compulsive Disorder: Proof-of-Concept
Rapid anti-OCD effects from a single intravenous dose of ketamine can persist for at least one week in some OCD patients with constant intrusive thoughts. This is the first randomized, controlled trial to demonstrate that a drug affecting glutamate neurotransmission can reduce OCD symptoms without the presence of an SRI and is consistent with a glutamatergic hypothesis of OCD
Migraines
Ketamine for Refractory Headache: A Retrospective Analysis
Ketamine provides potent analgesia in subanesthetic doses in chronic pain, and limited data suggest it may alleviate headaches in some patients. Maximum improvement occurred 4.56 days (mean) into treatment. Ketamine was associated with short-term headache relief with tolerable adverse events
Migraines
Ketamine may help treat migraine pain unresponsive to other therapies
The study of 61 patients found that almost 75 percent experienced an improvement in their migraine intensity after a three- to seven-day course of inpatient treatment with ketamine
Pain
Plasma inflammatory cytokines and treatment-resistant depression with comorbid pain: improvement by ketamine
Ketamine can address both physical and psychological pain. It's widely used as an analgesic, and many people with depression also experience physical pain. This study found that ketamine had a stronger anti-depressant effect in patients with treatment-resistant depression (TRD) and pain than with TRD alone
Pain
Ketamine Infusions for Chronic Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials
A metanalysis of studies examining ketamine's effect on pain. Among 696 studies assessed for eligibility, 7 met inclusion criteria. Evidence suggests that IV ketamine provides significant short-term analgesic benefit in patients with chronic refractory pain, with some evidence of a dose-response relationship
PTSD
Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial
Veterans and service members with PTSD who failed previous anti-depressant treatment were randomized to 8 infusions administered twice weekly of either placebo, low dose, or standard doses of ketamine. The standard ketamine dose ameliorated depression measured by the MADRS significantly more than placebo. Ketamine produced dose-related dissociative and psychotomimetic effects, which returned to baseline within two hours and were less pronounced with repeated administration. Secondary analyses suggested that the standard dose exerted rapid anti-depressant effects
PTSD
A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder
This small study demonstrated clear superiority of six intravenous infusions of ketamine compared with midazolam (a psychoactive control) over two weeks, with two-thirds of patients considered responders to ketamine compared with one-fifth of those receiving midazolam
PTSD
The Therapeutic Effects of Ketamine in Mental Health Disorders: A Narrative Review
In 2020, a retrospective study analyzed internet posts on the Bluelight website, a public forum intended to provide a platform for people to discuss their drug use. It evaluated the self-reported use of ketamine in patients with PTSD [49]. The results found that patients with self-perceived PTSD had decreased incidence of negative symptoms when using ketamine
Suicidal ideation
The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis
Suicide is a public health crisis with limited treatment options. The authors conducted a systematic review and individual participant data meta-analysis examining the effects of a single dose of ketamine on suicidal ideation. They concluded that ketamine rapidly reduced suicidal thoughts within one day and for up to 1 week in depressed patients with suicidal ideation.

"Ketamine is definitely applicable to people who may need some help with night terrors, but also is applicable to people who have, you know, a lot in their lives and are looking for a way to chill themselves out, you know, in a way that maybe they didn't expect."

 – Kelly

Treatment options for holistic wellness

Ketamine

Our foundational program: 6 intravenous infusions administered over 2-3 weeks under careful monitoring by our trained medical staff

Ketamine + Coaching

Our Healing Pathway option brings you together with an experienced psychedelic practitioner focused on self-empowerment, finding clarity, and dislodging blocks

Ketamine + Therapy

Work through challenging life issues with Ketamine Assisted Psychotherapy, our most involved program, with a licensed mental health counselor trained in psychedelic therapy

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