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Ketamine for OCD

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Ketamine is different from traditional anti-depressants

Depression, from mild to moderate to severe, responds very robustly to low-dose ketamine. If you are struggling with depression symptoms and have tried other treatments with sub-optimal results, ketamine could be effective for you.

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Over 80% of patients report at least a 50% reduction in symptoms at their first series of treatments

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An estimated 30.9% of those with Major Depressive Disorder can be defined as having Treatment Resistant Depression

OCD research

Effect
Study
Level of evidence
Magnitude of effect
Summary
OCD
Rapid anti-OCD effects from a single intravenous dose of ketamine can persist for at least one week in some OCD patients with constant intrusive thoughts. This is the first randomized, controlled trial to demonstrate that a drug affecting glutamate neurotransmission can reduce OCD symptoms without the presence of an SRI and is consistent with a glutamatergic hypothesis of OCD.

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